The gameplay is standard tower defence stuff. You create increasingly powerful (and costly) towers (the titular cubemen) in an attempt to curtail the enemy's assault into your base, whilst using cubes (awarded from destroying enemies) to build more. But here's where it differs from the rest of the bunch, and starts to get interesting: your cubemen move about freely. That's not to say that it becomes more of a real-time strategy game: your little guys can only move between predetermined points, but they can (and will) engage enemies whilst on the move. Adding to this is that the maps are fully 3D (again with a cubic style), so positioning cubemen becomes doubly important.